Host-pathogen interactions

Fusarium wilt of flax is the most destructive and widespread disease, both in the Russian Federation and in other countries.  Genome of F. oxysporum f. sp. lini, the main causative agent of this disease is not sequenced and the molecular mechanisms underpinning this infection are unknown. We use genomics  and bioinformatics to develop an effective long-term disease control strategy by selecting optimal combinations of resistance genes and to answer many fundamental questions about the mechanisms of interaction of flax and pathogen: Which fungus genomic regions and which genes are involved in the infection? How does Fusarium oxysporum f. sp. lini infect plants? What is the variability of infection related genomic regions? How does the host plant protect itself against infection and what are its resistance mechanisms? Which host plant genomic regions are involved in the resistance mechanism? How do the fungus virulence genes and plant resistance genes co-evolve? Does DNA methylation play an important role in the response of flax plants to infection?


Телефоны: +7 (812) 290-96-42
+7 (812) 290-96-45

Адрес: г. Санкт- Петербург, ул. Политехническая, 29АФ


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